The area later became part of a Mexican land grant, Rancho Corte de Madera del Presidio, operating as cattle and dairy ranches until the 1870s.
The depot's crowning achievement was the installation of a massive seven-mile, 6,000-ton submarine net across the Golden Gate entrance, completed before the Pearl Harbor attack.
Though briefly reactivated during the Korean War, the depot eventually closed in 1958, and portions of the property were converted to public parks.
[6] The modern research era began in 1961 when the U.S. Bureau of Sport Fisheries and Wildlife established a marine laboratory on site.
This period saw diverse scientific activities, including the Marine Minerals Technology Center's ocean floor research and Naval Electronics Facility operations.
The installation of an advanced seawater system in 1972 enabled sophisticated marine research, and in 1975 the facility became part of the Southwest Fisheries Center.
An approved master plan and certified environmental impact statement are required before the university can begin significant construction projects at the campus.