San Giacomo delle Segnate (Lower Mantovano: San Iàcum dli Sgnàdi) is a comune (municipality) in the Province of Mantua in the Italian region Lombardy, located about 160 kilometres (99 mi) southeast of Milan and about 30 kilometres (19 mi) southeast of Mantua.

Villa Arrigona was built between 1619 and 1622 on the commission of Count Pompeo Arrigoni, of the noble Arrigoni family, to the architect Antonio Maria Viani, already in the service of the Gonzagas of Mantua.

The villa, made up of several buildings, was a stately country residence and was usually inhabited seasonally.

Built on two floors with adjoining late Baroque oratory, park and cultivated land.

The façade is characterized by a tympanum reminiscent of Palazzo Te, under which the large stone family coat of arms stands out.