San Giovanni Grisostomo (English: Saint John Chrysostom) is a small church in the sestiere or neighborhood of Cannaregio, Venice.

The church was founded in 1080, destroyed by fire in 1475, then rebuilt starting in 1497 by Mauro Codussi and his son, Domenico.

Behind the façade are hung two canvasses, formerly organ doors, by Giovanni Mansueti depicting Saints Onuphrius, Agatha, Andrew and John Chrysostom.

Onuphrius was the co-titular patron saint who was revered by the confraternity of the Tentori (dyers of fabrics, covers, and sheets).

On the wall of the apse is a series of canvases on the life of Saint John Chrysostom and Christ.