San Miguel also includes the Isla de Convalecencia, the largest island in the Pasig River, which is home to the Hospício de San José, Manila's oldest Catholic welfare institution.

Malacañang Palace, the seat of the Government of the Philippines and official residence of the President of the Philippines, is located in the neighborhood, and outside the Palace gates is Mendiola Street, a popular site for protests against the government.

The brewery's buildings were demolished after the property was transferred to the Philippine government, and it today forms part of the Palace complex.

Casa Roces is located in the district of San Miguel, Manila right across Malacañan Palace, the official residence of the President of the Republic of the Philippines.

Casa Roces was designed in the Pre-war modernist style with Art Deco articulation using a variety of construction materials which includes reinforced concrete, wood and masonry.