San Miguel Topilejo is a community in the borough of Tlalpan, Mexico City, Mexico.

The San Miguel Arcángel temple is in this community.

Corn, oat, and vegetable cultivation form the backbone of its economy.

The Corn Fair (feria del elote) is held here.

[1] Escuela Preparatoria Tlalpan II "Otilio Montaño" is located in the community.