The Chiesa di San Salvatore (of the Holy Savior) is a church in Venice, northern Italy.

The church was first consecrated in 1177 by Pope Alexander III shortly after his reconciliation with Emperor Frederick Barbarossa at nearby San Marco.

The present church, however, was begun in around 1508 by Giorgio Spavento and continued after his death the following year by Tullio Lombardo, Vincenzo Scamozzi and possibly Jacopo Sansovino.

Adjoining the church is the former monastery, now the offices of the telephone company, which still contain Sansovino's magnificent cloisters.

It derived from a bombardment in 1849 by Austrian forces in the port of Marghera, of the independent republic which had been proclaimed by Daniele Manin.