San Sisto is a Renaissance style, Roman Catholic church, located on the Via of the same name in north-central Piacenza, Region of Emilia Romagna, Italy.
The church and an adjacent convent and hospital were founded in 874 by Queen Angilberga, wife of the Emperor Louis II.
At the end of the Nave, in the choir of the apse is a copy of the Raphael's Sistine Madonna attributed to Pietro Antonio Avanzini.
[2] To the great loss of Piacenza, the Benedictines pawned off the original in 1754 to Augustus III, King of Poland for the lordly sum of twelve thousand zecchini.
The painting is now one of the masterpieces on display at the Gemäldegalerie in Dresden;[3] To the left of the transept is the altar and tomb dedicated to Margaret of Parma, designed by Simone Moschino.