The church is named after San Tommaso Apostolo (Saint Thomas the Apostle).

For example, The Baroque architecture layout we see today was completed in 1652 by Giuseppe Sardi, using a design originally by Baldassare Longhena.

The main altar once had statues of Saints Thomas and Peter (1616) sculpted in marble by Girolamo Campagna.

It also had a main altarpiece depicting Crucifixion Scene by Andrea Vicentino, who also had a number of other works inside the church.

On the left side above a portal, is a 15th-century relief of the Madonna della Misericordia (Our Lady of Mercy).