San Ysidro is a village in Sandoval County, New Mexico, United States.

The village is near the junction of U.S. Highway 550 and New Mexico State Road 4, at the south end of the Jemez Valley.

The village has been a farming community since 1699 when Juan Trujillo established a settlement named for San Ysidro, or Saint Isidore the Farmer.

An annual San Ysidro Fiesta Day is held each year in mid-May.

In 2007, the exterior sets for the Taylor Hackford film Love Ranch were built just outside of San Ysidro on Highway 550.