Sanada Nobutsuna (真田 信綱, 1537 – June 29, 1575) was a Japanese samurai of the Sengoku period.

[1] He was the eldest son of Sanada Yukitaka, a castle lord in Shinano Province, who by the time of his son's coming-of-age, had pledged his loyalty to the Takeda.

[3] According to Shinchō Kōki, Nobutsuna served as a member of the rearguard in the retreat and was killed.

[4] After Nobutsuna's death his younger brother, Masayuki took the clan leadership.

[3] Nobutsuna's daughter Seiin-in was Sanada Nobuyuki (Masayuki's elder son)'s first wife.