Sandown is notable because when in 1793-94 she carried slaves from Sierra Leone to Jamaica, her master, Captain Samuel Gamble, kept a detailed log with profuse illustrations.

Lloyd's Register for 1793 shows her master changing from W. Snow to S. Gambell, her owner from J. St Barbe to Cameron, and her trade from London–Straits [of Gibraltar] to Cork–Africa.

[8] A group of London investors had chartered Sandown for £125 per month to sail to Africa, acquire captives, and then deliver them to the West Indies.

When she arrived in the West Indies, the contract would end, with the owners' agent taking over the ship, captives, and cargo.

[4][b] On 14 January 1794, the enslaved people on board staged an uprising that left eight or ten captives dead before it was suppressed.