Sandra C. Cano (born 1983) is an American politician from the state of Rhode Island.

She won a special election on April 3, 2018, to succeed James Doyle II in the Rhode Island Senate.

[4] On January 12, 2021, Cano was appointed chairperson of the Senate Committee on Education for the 2021-2022 session.

[6] Cano resigned from the Rhode Island Senate in September 2024 in order to pursue a career opportunity outside of the legislature.

[8] Cano's fiance, James Diossa, is the general treasurer of Rhode Island.