Sandra Sassine (born September 28, 1979) is a Canadian fencer.

She competed in the individual and team sabre events at the 2008 Summer Olympics.

In the women's sabre in 2008, she competed in section 3, beating Elvira Wood in the first round, but was eliminated in the second round by gold medalist Mariel Zagunis.

She competed in the women's individual sabre event at the 2012 Summer Olympics where she lost to Aleksandra Socha in the first round.

This biographical article related to fencing in Canada is a stub.