Born in Montreal, Quebec, Grande began his career in Italy, He played four years with U.S.Frenter Larino and Potenza and Frosinone in the late 1990s and early 2000s.
He helped the Impact qualify for the CONCACAF Champions League quarter finals, playing six games in the tournament.
[3] In 2012, Sandro Grande signed a contract with the FC St-Léonard of the Première Ligue de Soccer du Québec.
Grande made his debut for the Canada national team in a September 2004 World Cup qualification match against Costa Rica and has earned a total of 12 caps, scoring 1 goal.
He was released from the position a day after due to backlash over comments Grande made on Twitter in 2012, following the attempted assassination of Quebec premier Pauline Marois.