Sanford is a village in Midland County in the U.S. state of Michigan.

Douglass Houghton, the state surveyor and geologist, supervised sinking the shaft of the well.

Romig identifies Jay F. Hamilton as the first postmaster of "Sanfordville" on June 23, 1871, while the Portrait and biographical album of Midland county, Mich. lists Phineas Hamilton as the first postmaster.

[5] In 1982, Sanford voters approved the repeal of its incorporation, but a Michigan court overturned the election results on the grounds that it should have been presented as one proposal instead of two.

[6][7] Sanford is in central Midland County, on the eastern side of Jerome Township.

U.S. Route 10, a four-lane freeway, passes through the north side of the village, connecting Midland and Coleman.

M-30 (Michigan highway) runs along the eastern edge of the village, leading south 20 miles (32 km) to Merrill and north 48 miles (77 km) to West Branch.

30.1% of all households were made up of individuals, and 11.7% had someone living alone who was 65 years of age or older.

25.9% of all households were made up of individuals, and 9.2% had someone living alone who was 65 years of age or older.