[1] The principal island is also named Sangihe, on which lies the main town of Tahuna.

[4] It is believed that inhabitants of the Sangihe Islands migrated from the Philippines archipelago, especially from Mindanao.

The culture of the native people in the islands has been influenced by Hinduism, Buddhism, and later, when the region was under Spanish hegemony, Christianity such as Kingdom of Manganitu under Bataha Santiago.

Main economic center of the regency, Tahuna, has average elevation of 250 metres above sea level.

[4] As with most regions in Indonesia the Regency has a tropical climate and is affected by monsoons, with the rainy season experienced between September and November.

The region experiences high moisture levels ranging between 81 and 87% with average yearly of 83.6%.

Meanwhile, heads of districts are appointed directly by the regent with the recommendation of regency secretary.

[11] Main economic activity in the regency is fisheries, which contributes to 27.96% of its gross regional product.

Other significant industries include construction, warehouse, and financial and insurance services.

[12] There has been a sharp decline in agricultural output, such as ginger production from 6,499 kilograms in 2019 to 2,887 in 2020 and galanga from 2,562 to 1,215.

[14][13] 83% of the regency population are Protestants, followed by 16% of Muslims, 0.84% of Catholics, and 0.01% of other religions such as Hindu and Buddhism.

There are several higher education institutions, including state-owned Nusa Utara Polytech, Didaskalos Christianity College of Sangihe, and Monetary & Banking GMIST Academy.

It created 2,556 graduates in 2020 and offered diploma in nursery, fishery-related programs such as maritime resources management, and computer and communication.

It was created first in 2006 with assistance of Ratulangi University and the Ministry of Education and Culture in a previously regency-owned nursery academy and has since been expanded.

Being an archipelago, water transport is important for movement within the regency and to outside regions.

The regency is served by Sea Toll Program to help reduce price disparity in the region.