This large church, and its adjacent Dominican order convent, was located next to the Ponte di Sant'Agostino.
It was described by the historian Pietro Selvatico as "without doubt the most beautiful medieval building in Padua after the Basilica di Sant'Antonio".
The architect was Leonardo Murario, called il Rocalica, and was built between 1226 and 1275 under the patronage of Nicolò di Boccassio, Bishop of Padua and future pope Benedict XI.
Some of the columns were reused by the architect Giuseppe Jappelli, in the building now used by the Liceo Artistico Pietro Selvatico.
The building is now the caserma Piave, where a fragment of a fresco by Guariento, originally in the church was discovered.