Sant'Antonio Abate is a Romanesque-style, Roman Catholic church, located facing Piazza Sant'Antonio in Pisa, region of Tuscany, Italy.

The church was founded in 1341 with an adjacent convent.

The inferior façade, in two colors of marble, was the design product of Lupo, Giovanni di Gante, and Simone di Matteo of Siena.

On a rear wall of the convent, facing Via Zandonai, is a vast 1989 mural, titled Tuttomondo, by Keith Haring.

The mural was one of the last public works by Haring.