Sant'Isidoro a Capo le Case is a Catholic church, monastic complex and college run by the Franciscan Order in the Ludovisi district on the Pincian Hill in Rome.

The monastery was founded by a gift from the nobleman Ottaviano Vestri di Barbiano, as shown in a bull of pope Urban VIII of 1625.

The monastery was dissolved for a time by Napoleon I and from 1810 to 1820 its monastic buildings housed the artistic colony known as the Nazarenes.

[6] In 2008, the Master General of the Franciscan Order transferred the convent and activities of St. Bonaventure in Grottaferrata, with an important library, here.

The facade is by Carlo Francesco Bizzaccheri (1704-1705) using the double-ramped staircase and portico already completed by Domenico Castelli.