Santa Catarina (English: Saint Catherine) is a former parish (freguesia) in the municipality of Lisbon, Portugal.

Its history was linked to Portuguese discoveries in the 14th and 15th Century, and is characterized by a diverse historical, sociological and cultural influence that mingled the aristocratic and popular.

The administrative limits have suffered successive alterations, the last of which (1959) caused controversy by removing many of the emblematic infrastructures of the parish.

Many figures linked to the cultural or political life of the city (and the country) lived for a time in the parish, including Sebastião José de Carvalho e Melo, Manuel Maria Barbosa du Bocage, Almeida Garrett, Alexandre Herculano and Camilo Castelo Branco.

Also, in 1847 (on Rua de São Boaventura) Maria Amália Vaz de Carvalho was born (and also lived and died), a champion of women's rights, who affirmed, The parish is part of a mountainous area, part of the Bairro Alto, that descends south toward the Tejo, and west to toward the parish of São Bento, cutting the Calçada do Combro, supposedly the principal roadway in the formation of Lisbon, and where today is concentrated the largest group of architecturally significant buildings in the region.