Santa Cruz, is the primary tourist neighborhood of Seville, Spain, and the former Jewish quarter of the medieval city.
In the 18th century, the neighborhood underwent a major process of urban renewal, including the conversion of a former synagogue into the current Church of Saint Bartholomew.
During the Napoleonic Wars the church was demolished as part of an urban renewal scheme, the old floor remained as the present plaza.
The Barrio de Santa Cruz is a labyrinth of narrow streets and alleys dating back to the old judería.
The Callejón del Agua, an alley parallel to the city walls, was once the route along which water was brought to the royal Alcázar of Seville, and was once the home of the American writer Washington Irving, as is recorded by a plaque made by Mariano Benlliure.