Santa Cruz Xitla is a town and municipality in Oaxaca in south-western Mexico.

It is part of the Miahuatlán District in the south of the Sierra Sur Region.

[1] Municipal president Pedro Modesto Santos died of COVID-19 in September 2020.

He was the eighth municipal president in Oaxaca to die of the virus.

This article about a location in the Mexican state of Oaxaca is a stub.