Santa Giuletta is a comune (municipality) in the Province of Pavia in the Italian region Lombardy, located about 50 km south of Milan and about 15 km south of Pavia.

[3] Santa Giuletta borders the following municipalities: Barbianello, Mornico Losana, Pietra de' Giorgi, Pinarolo Po, Redavalle, Robecco Pavese, Torricella Verzate.

Santa Giuletta is situated at the end of the Apennines chain.

The village has a railway station on the line Alessandria-Voghera-piacenza.

The area in which Santa Giuletta is located is known as "Oltrepo Pavese".