Santa Maria is an impact crater on Mars, located at 2.172°S, 5.445°W within the Meridiani Planum extraterrestrial plain, lying situated within the Margaritifer Sinus quadrangle (MC-19) region.

This geological feature was first visited by the Mars Exploration Rover Opportunity.

Its name has not been officially recognized by the Working Group for Planetary System Nomenclature.

[2] The rover was positioned at the south eastern rim, where it took several images and prepared for the oncoming Solar Conjunction.

[3] Communications resumed around a week later, and the rover performed several in-situ studies of the rocks "Luis de Torres" and "Ruiz Garcia".