It is famous as the location of the Brancacci Chapel housing outstanding Renaissance frescoes by Masaccio and Masolino da Panicale, later finished by Filippino Lippi.
The complex was enlarged a first time in 1328 and again in 1464, when the capitular hall and the refectory added, though the church maintained the Latin Cross, one nave plan.
The fire did not touch the sacristy: therefore have survived the Stories of St. Cecilia attributed to Lippo d'Andrea (c. 1400) and the marble monument of Pier Soderini by Benedetto da Rovezzano (1511–1513).
The Brancacci Chapel also survived the fire, and was saved by the subsequent restoration by the intervention of a Florentine noblewoman who was firmly opposed to the covering of the frescoes.
[3] The cycle of the lunettes in the cloister was frescoed in the 17th and 18th-century with episodes from the Carmelite history painted by the Florentine artists Galeazzo and Giovan Battista Ghidoni, Domenico Bettini, Cosimo Ulivelli and Antonio Nicola Pillori.
Most of the artworks are therefore fragmentary: these include the Bestowal of the Carmelite Rule by Filippo Lippi and the Last Supper by Alessandro Allori 1582, and remains of works from other chapels by Pietro Nelli and Gherardo Starnina.