A church at the site was first erected in 1479 to house a Marian image painted on the outer walls of the city at that time.
The present structure was built in 1661 and renamed by the Roman Confraternity of the Gonfalone.
Their names and the chains putatively used during their imprisonment were moved to the church of San Girolamo della Certosa.
Most of the movable artworks were moved to Casa del Clero in the monastery of Sant'Agostino.
This article about a Roman Catholic church building in Italy is a stub.