Santa Maria della Salute (English: Saint Mary of Health; Venetian: Bazéłega de Santa Maria de ła Sałute), commonly known simply as La Salute (Italian: [la saˈlute]), is a Roman Catholic church and minor basilica located at the Punta della Dogana in the Dorsoduro sestiere of the city of Venice, Italy.

As a votive offering for the city's deliverance from the pestilence, the Republic of Venice vowed to build and dedicate a church to Our Lady of Health.

The dome of the Salute was an important addition to the Venice skyline and soon became emblematic of the city, appearing in artworks both by locals, such as Canaletto and Francesco Guardi, and visitors, such as J. M. W. Turner and John Singer Sargent.

The end of the 1630 plague was attributed to the intercession of an icon of the Virgin Mary that was brought to Venice in 1670 by sea captain Francesco Morosini as a trophy following the peace terms obtained with the Turks in the war of Candia (present-day Crete).

The desire to create a suitable monument at a place that allows for easy processional access from Piazza San Marco led senators to select the present site from among eight potential locations.

Of the proposals still extant, Belli's and Smeraldi's original plans were conventional counter-reformation linear churches, resembling Palladio's Redentore and San Giorgio Maggiore, while Varotari's was a sketchy geometrical abstraction.

While Longhena saw the structure as crown-like, the decorative circular building makes it seem more like a reliquary, a ciborium, and embroidered inverted chalice that shelters the city's piety.

Built on a platform made of 1,000,000 wooden piles, it is constructed of Istrian stone and marmorino (brick covered with marble dust).

The interior has its architectural elements demarcated by the coloration of the material, and the central nave with its ring of saints atop a balustrade is a novel design.

The statuary group at the high altar, depicting The Queen of Heaven expelling the Plague (1670) is a theatrical Baroque masterpiece by the Flemish sculptor Josse de Corte.

The dome of the Salute was an important addition to the Venetian skyline and soon became emblematic of the city, inspiring painters like Canaletto, J. M. W. Turner, Claude Monet, John Singer Sargent, Francesco Guardi, and the Serbian poet Laza Kostić to write a poem of the same title.