Santa Maria Assunta is a Renaissance church in Genoa, Italy.

The church is on the Greek cross plan with four similar façades on each side.

There are five domes and two squared-plan bell towers (four in the original design) at the Neoclassic main façade.

Along the walls, the statues of apostles and doctors of the church were completed by 1740 by Francesco Schiaffino.

The presbytery and main altar have paintings depicting of the Last Supper and Flight to Egypt by Giuseppe Palmieri.