Established in 1792, it is under the jurisdiction of the Diocese of San Pablo and is the second oldest named parish dedicated to Saint Rose of Lima in the Philippines.

[3] The Saint Rose of Lima Parish was built in the year 1792 with the arrival of Spanish Catholic priest, Francisco Favie.

[citation needed] The first Mass was held on August 30, 1812, in honor of the patron saint,⁣⁣ Rose of Lima, with Francisco Favie, the first parish priest.

In 1796, Spanish friars built the present church building with labor from China who later became descendants of the old Chinese families in Santa Rosa including the Lijauco's and the Tiongco's.

[sentence fragment] Mariano Perlas Sr., an indigenous Santa Rosa painter in the early 20th century, was inspired to paint the church's ceiling by Andres Tejedor (Oct. 1916 – Feb. 1926), a Spanish priest of the Dominican Order.