Santa Sofía is a town and municipality in the Department of Boyacá, part of the subregion of the Ricaurte Province, Colombia.

The name was changed in 1906 to Santa Sofía, because mail that was meant to go to Guateque, in southern Boyacá, was accidentally delivered in Guatoque.

[6] Within the boundaries of the municipalities is located the Hoyo de la Romera, a sinkhole where unfaithful Muisca women were punished.

Main economical activities of Santa Sofía are livestock farming and agriculture, especially curuba, tomatoes and strawberries.

[1] Santa Sofía is a rural community that gives access to the Guatoque Páramo and the Paso del Ángel, an ancient indigenous road.