Sante Pacini (1735 – c. 1790) was an Italian painter and engraver active mostly in Tuscany in an early Neoclassic style.
Sante was born in Florence, and was a pupil of Ignazio Hugford.
He was the son of Michele Pacini, an engraver working for Anton Domenico Gabbiani.
Sante made engravings for Cento Pensieri Diversi by Gabbiani.
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