After the end of the series, Millan was hired by the same production company to play the role of Sergio Antúnez in the sitcom Siete Vidas, also aired on Telecinco.

Capitalising on his television fame, he started a career in cinema: Vivancos 3 (2003), Di que sí (2004) and his first dramatic role, Amor idiota (2005), which was followed by comedy Va a ser que nadie es perfecto (2006).

The next year, he produced (with El Terrat) and starred in the TV series Divinos, aired on Antena 3 and cancelled after two episodes due to poor ratings.

In 2012, Millán starred in the drama television series Frágiles on Telecinco, and was hired by variety show El Hormiguero on Antena 3 as a new collaborator.

[2] In 2014, the comedy television series El chiringuito de Pepe premiered on Telecinco, starred by Millán, Jesús Bonilla and Blanca Portillo.