Santiago Manuin Valera (1 January 1957 – 1 July 2020) was a Peruvian human rights activist and indigenous leader.
He was a key leader of the Aguaruna people in Peru.
He was President of the Committee for the Struggle for Respect for Indigenous Peoples of Condorcanqui.
During a police crackdown on dissenters in 2009, he was shot, but survived the encounter.
He and other activists were blocking a road to protest the destruction of the Amazon rainforest.