Santiago South Regional Football Association (Portuguese: Associação Regional de Futebol de Santiago Sul, abbreviation: ARFSS, not commonly as ARFSZS) is a football (soccer) association covering the south of the island of Santiago, it is an affiliate of the Cape Verdean Football Federation.
The association covers the municipalities of Praia, Ribeira Grande de Santiago and São Domingos.
Its logo has an edged crescented crest and features a football (soccer ball) and on the bottom are the Portuguese language acronym ARFSS.
When it was created it wholly covered the Praia until the formation or Ribeira Grande de Santiago in 2005 that split the western part of the municipality.
Two additional registered clubs started to play in the lowest division for the 2016–17 season and now totals ten with 22 overall.