Santo Bugito is an American animated television series produced and developed by Klasky-Csupo for CBS and created by Arlene Klasky.

Notable achievements of this series included a revival of the insect-community genre (little of which had been seen since Mr. Bug Goes to Town), and voice cameos from well known performers such as Jim Belushi.

The regular cast included Tony Plana, William Sanderson, Henry Gibson, George Kennedy, Cheech Marin and Joan Van Ark.

Carmen De La Antchez (Marabina Jaimes) is the show's protagonist, an ant who runs a restaurant in the town with her husband, Paco (Tony Plana).

The town is populated by other insects, including two brash American flies, Clem (William Sanderson) and Burt (Michael Stanton), a hyperactive flea named Lencho (Cheech Marin), a cynical artist termite named Eaton Woode (Charles Adler), a butterfly named Rosa (Candi Milo) and her boyfriend Miguel who is still in his cocoon, Amelia (Joan Van Ark), an enthusiastic damselfly, Ralph, a large friendly ladybug with a deep voice (George Kennedy) and a praying mantis professor who occasionally interrupts the show to give dull educational lectures, but is usually pushed off-screen by another character.