It focuses on three microscopic Sea-Monkeys – Dave (Rob LaBelle), Bill (Peter Pitofsky) and Aquarius (Sean Whalen) – who have been enlarged to human size by their benefactor, the Professor (Howie Mandel).
Howie Mandel got the idea for the show after his daughter wanted to get some brine shrimp pets known as Sea Monkeys, which he also had as a child.
The plot revolved around the notion that the Professor had accidentally enlarged three sea monkeys to human size, and plotlines followed their ensuing comical ineptness in the world.
Each Sea Monkey displayed a certain odd character trait: Aquarius could not keep a secret, Bill was afraid of Imperial style beards, and Dave would grow excited at the sound of polka music.
After the show's cancellation, it was replaced by Beakman's World, with Schneider playing the lead female role in that series as well.