The Church of the Santo Sepolcro (Italian: Chiesa del Santo Sepolcro, literally "Church of the Holy Sepulchre") is a religious edifice in Pisa, Tuscany, Italy.
The central tambour, supported by eight ogival arches, is super-elevated and is surmounted by a conic cusp.
The attribution to the Holy Sepulchre is a reference to the latter's relics which were carried in Pisa by archbishop Dagobert after his participation to the First Crusade.
What remains include a bust-reliquary of St. Ubaldesca (15th century) with a pail which, according to the tradition, belonged to the saint; the tombstone of Marie Mancini, Mazarin's niece; and a 15th-century panel of the Madonna with Child.
The unfinished small bell tower is in Pisane-Romanesque style, with rectangular plan.