Sapadbizes (Σαπαδβιζης), also Sapalbizes or Sapaleizis, was a ruler of western Bactria, sometimes linked to the Yuezhi.
This places him after Phraates IV (40 BC) and before the debasement of coinage in Northwest India (AD 20).
It is likely that Sapadbizes and these other rulers were descendants of tribes who had invaded Bactria and imitated the coins of the last Greco-Bactrian kings.
However, scholars surmise that his kingdom was conquered by Kujula Kadphises, during the latter's war with Parthia, and absorbed into the Kushan Empire, probably about the year 30 AD.
A coin of Sapadbizes was discovered in the burial site of Tillya Tepe.