Costa went public with the bid following a podcast interview in which Innamorato was quoted saying, "My district, which I know is like white working class, poor folk, who are racist, because it's so much easier for them to look to their side and say, 'I'm going to blame that person.

[8] In 2020, Innamorato was initially opposed by Stephen Zappala III, the son of the Allegheny County District Attorney, for the Democratic Party nomination.

[22] Innamorato opposes hydraulic fracturing, citing many public health concerns in communities near drilling sites and refineries.

[23] She has voted against legislation to grant tax exemptions and incentives to new petrochemical plants, labeling such proposals "corporate welfare".

"[24][25][26] Innamorato has stated that she has worked to draft legislation to prevent the dumping of chemicals and waste water used in hydraulic fracturing into sewage treatments plants and public waterways, due to alleged radioactive contamination.

[32] Innamorato has spoken publicly in favor of instituting a Medicare-for-All type universal health insurance program for Pennsylvania.

[33][34] Innamorato sponsored legislation intending to end the practice that allowed medical students in Pennsylvania to perform pelvic examinations on unconscious women without their consent.

[36][37] She favors what she terms "harm reduction strategies" to combat the epidemic; including policies such as decriminalization and rehabilitation for drug users.

[45] Innamorato supported legislation giving Second Class cities in Pennsylvania the legal authority to freeze property taxes for long-time and elderly residents.

[49] Innamorato issued a joint statement on October 7, 2024 with Summer Lee (PA-12) and Pittsburgh Mayor Ed Gainey which was criticized by Jewish groups for being anti-semetic.

Rabbi Yitzi Genack called the statement "tone deaf" given the "false equivalence between Jews defending themselves and attacks and murders and rapes and burnings of Jewish people".

[50] She condemned the DSA for their statement describing the 2023 Hamas-led attack on Israel as "inevitable" due to "the conditions imposed by Israeli occupation".

She countered the sentiment, emphasizing Israel's right to self defense and affirmed her solidarity with the Jewish people as well as the direct victims of the attack.