In 2006, Lowes started playing keyboards for David Potts, Jim Noir, and on King Creosote's album KC Rules OK.

In the same year Lowes joined Half Cousin and sang backing vocals on their second album, Iodine: she also played keyboards live for the band.

After five years of session work Lowes released her first solo mini album Tomorrow's Laughter on Red Deer Club Records in 2008.

In February 2011 she rejoined The Earlies to back King Creosote a further time and record the live album Lancashire Bits of Strange.

In April 2012 Lowes joined the live band for Marina and the Diamonds for her second album release Electra Heart and supported Coldplay on the Europe and America tours.