She went on to study at the University of California, Berkeley, receiving her MFA in studio art and attended the Skowhegan School of Painting and Sculpture in 2006.
[6] Quinn Latimer described Cain's work: "They court seemingly bad ideas—drawings sport feathers and doilies; installations feature eggs and hippy art teacher-like fabric swatches—and then transform them so deftly into serious painting that it can take a minute to understand what you’re looking at.
"[7] In 2011, Cain collaborated with George Herms at the Orange County Museum of Art, where the curator Sarah Bancroft wrote for the accompanying catalog that the two artists share "an interest in language and a frustration over its limits in describing abstract work".
[9] In 2019, she completed her first major permanent public work at San Francisco International Airport: a 150-foot stained glass window with 270 colors, framed in soldered zinc, which was "painstakingly arranged so that no two adjoining fragments are the same shade.
Her attack and command of both physical and pictorial space is incisive yet wildly generous, leaving the viewer with no singular place to stand or look.