Pritchard has held leadership positions in academic institutions, influencing library administration, digital initiatives, and scholarly research.

Her expertise encompasses diverse areas, including women studies, feminism, collection development, technology integration, scholarly communication, and international library partnerships.

Accomplishments over her tenure included expanding the collections to over 7 million items, developing a 20-year strategic space plan, construction of a high-density climate controlled shelving facility, transformation of the Mudd Library building, establishing positions for digital humanities and data management, new collaborations with other campus entities such as the Block Museum of Art, overseeing an improved business model for the University Press, and formally confirming the faculty status of librarians.

[12] Pritchard was founding board member of portal – Libraries and the Academy published by the Johns Hopkins University Press and editor from 2009-2014.

[19] Since 2023, Pritchard has served as President of the Caxton Club in Chicago, where she has been instrumental in promoting bibliophily and the appreciation of fine printing through various events and initiatives.