[7] From 2001 to 2002, she worked for Add-Vision in Scotts Valley as a research scientist,[7] and was part of the team that built the first screen-printed polymer light emitting diodes.

[8] Tuttle received a M.Sc and M.Phil in astronomy from Columbia University in 2006 and 2007,[9] and obtained her Ph.D in 2010,[7] working with David Schiminovich on the Faint Intergalactic medium Redshifted Emission Balloon (FIREBall).

[5][10] Tuttle's research applies novel hardware approaches to spectrograph instrumentation design, particularly aimed to isolate star formation regulation in galaxies through emission and infall from the interstellar medium.

[26][27] Tuttle has also contributed to American Astronomical Society workshops and supported new guidelines to build a more diverse and inclusive environment.

[28] Tuttle was a board member and hotline operator for the Lilith Fund until 2016, a reproductive-rights nonprofit that provides Texas women with financial support for obtaining abortions.