Sarcoxie is a city in Jasper County, Missouri, United States.

Sarcoxie was platted in the early 1830s, and it was originally called Centerville from its location upon Center Creek.

[5] In 1839, the settlement was renamed in honor of Sarcoxie, a chief of the Delaware Indians who had settled near a spring in the present town limits.

[8] During the start of the Civil War in 1861, Franz Sigel's independent command passed through Sarcoxie on June 28 before attempting to attack the separated commands of Sterling Price and Missouri Governor and General Claiborne Fox Jackson.

Price was rumored to be at Pool's Prairie, moving to the Confederate forces in Northwest Arkansas.

[9] The Cave Spring School and Cave Spring Cemetery and Sarcoxie Public Square Historic District are listed on the National Register of Historic Places listings in Jasper County, Missouri.

[10][11] According to the United States Census Bureau, the city has a total area of 1.08 square miles (2.80 km2), all land.

29.7% of all households were made up of individuals, and 12.6% had someone living alone who was 65 years of age or older.