Sargis Zakarian (Georgian: სარგის მხარგრძელი, romanized: sargis mkhargrdzeli; Armenian: Սարգիս Զաքարյան) was a founder of the Zakarid dynasty line.

He was a Court official of the Kingdom of Georgia, holding the offices of Amirspasalar (Commander-in-Chief) for Queen Tamar of Georgia during the late 12th century.

Sargis rose to prominence at the Georgian court in 1177, when he supported George III of Georgia during a revolt of his feudal lords.

[3] His son Zakare II Zakarian would inherit the title a few years later, from 1191.

[3][4] Sargis appears in various inscriptions of the time, such as the dedicatory inscription for the repair of the Church of St. Amenaprkitch in Sanahin Monastery and the construction of a gavit adjoining it, by Abbot Yovhannēs in 1181:[6] In the year 630 (ie 1181 CE), at the time of the victorious king Georg, and amirspasalar Sargis and his sons Zak‘arē and Iwanē, and amira K‘urd, I, Yovannēs, Abbot of the holy monastery (re)built this once existing church and a gawit‘ from its foundations, with the help of amir K‘urd and the great vardapet Grigor and Christ God, with great hope...[6]His wife was named Saakdukht Artsruni, of the House of Artsunids, their children were: