He is the founder, frontman and "anchor"[2] of the industrial band KMFDM.

[3] Keyboard Magazine wrote of him, "You won't find a more imaginative or effective keyboardist on the hard-core scene.

Konietzko has formed a number of side-projects: He has re-mixed acts including Metallica, Megadeth, White Zombie, Rammstein, Love & Rockets, Kittie, Die Krupps, Flotsam & Jetsam, Living Colour, Mindless Self Indulgence, Combichrist, Young Gods, and Pig.

Sascha Konietzko lived in the United States from 1991[5] to 2007, dividing his time among Chicago, New York City, and Seattle before moving back to his hometown of Hamburg, Germany.

Konietzko married fellow KMFDM member Lucia Cifarelli in 2005.