The Satilla River rises in Ben Hill County, Georgia, United States, near the town of Fitzgerald, and flows in a mostly easterly direction to the Atlantic Ocean.

The Satilla drains almost 4,000 square miles (10,000 km2) of land, all of it in the coastal plain of southeastern Georgia.

[2][3] The Satilla enters the Atlantic Ocean about 10 miles (16 km) south of Brunswick, at the 31st parallel north.

[5] The Satilla River is one of the few places in Georgia for observing nesting sites of brown pelicans.

[6] In May 2010, the city of Waycross purchased the Bandalong Litter Trap and installed it in Tebeau Creek, a tributary of the Satilla River.