These routes parallel the New York State Thruway (Interstate 87), which passes through the town just west of the village of Saugerties.

In the 1650s, Barent Cornelis Volge operated a sawmill on the Sawyer's Kill, supplying lumber for the manor of Rensselaerswick.

[4] In April 1677, Governor Edmund Andros purchased land from the Esopus Indian Kaelcop, chief of the Amorgarickakan band, for the price of a piece of cloth, a blanket, some coarse fiber, a loaf of bread, and a shirt.

[5] The Mynderse House was built by John Persen, formerly of Kingston, an early mill owner, circa 1685.

[3] In October 1710, three hundred families who had immigrated to England from the Palatine region of Germany established camps on the east and west side of the Hudson.

In 1998, a monument commemorating their arrival was erected on the lawn of St. Paul's Lutheran Church in West Camp.

[5] Sometime before 1730, the Katsbaan area northeast of the village was settled by Dutch farmers from Kingston and Palatines from the "Camps".

During the American Revolution, a British Squadron laid anchor at Saugerties from October 18–22, 1777, while raiding parties burned Clermont and Belvedere, across the Hudson River.

Barclay, who had business relationships with Robert L. Livingston, had a dam constructed on the Esopus Creek near today's 9W bridge.

Part of the Sheffield mill complex, formerly a blank book bindery and envelope factory, has been renovated as senior citizen housing.

At one time, 2,000 men were employed in quarrying, dressing and shipping about one and a half million dollars’ worth of blue stone annually from Glasco, Malden, and Saugerties.

In the early hours of November 9, 1879, the steamer Ansonia of the Saugerties Line ran against the Lighthouse dock on its return trip from New York, smashing the paddle wheel.

In 1889 Robert A. Snyder, John and George Seaman, Henry L. Finger, and James and William Maxwell started the "Saugerties and New York Steamboat Company".

[6] In 1892, the steamboats M. Martin and Tremper arrived at Saugerties at the same time, and collided near the lighthouse as each tried to get to the dock first.

In 1903, the steamboat Saugerties burned to the waterline, and the charred remains were scuttled in the cove north of the lighthouse.

In fact, in the late 1940s and early 1950s, the principal trumpet/solo chair of nearly every major symphony orchestra and concert band in The United States was held by a Williams student.

The Band began to create their distinctive sound during 1967 when they improvised and recorded with Bob Dylan a huge number of cover songs and original Dylan material in the basement of a pink house in West Saugerties, New York, located at 56 Parnassus Lane (formerly 2188 Stoll Road).

By the end of 1967 the Band felt it was time to step out of Dylan's shadow and make their own statement.

[15] The Hudson Valley Garlic Festival was established in 1989 by Pat Reppert of Shale Hill Farm and Herb Gardens.

They occupy 200 acres (0.81 km2) of land and have a 10-ring, Olympic-sized horse show facility in central Saugerties.

Hundreds were left without food and water when their cars became stuck in the muck that dominated the camp ground.

Catholic laborers, principally quarrymen of Fish Creek, also known as "The Clove", were accustomed to go on Sundays to St. Mary of the Snow, in the village, for Mass, and sometimes disorders ensued.

At that time the Saugerties congregation was served by Father Michael Gilbride, pastor in Hudson.

Mr. Russell, owner of the quarries offered Gilbride land for a church, and St. John the Evangelist was established.

[17] Construction began on the original lighthouse in 1835 to guide ships away from shallows and into Esopus Creek.

In 1873, a lantern room made out of cast-iron was installed with an iron-plate walkway that wrapped around for cleaning the outside panels of glass.

In 2016, a Kingston Creative study of social media data found that the Catskill Animal Sanctuary, Opus 40, and HITS were leading drivers of tourism, by virtue of mentions on instagram.