He went on to beat three unbeaten fighters (Callum Smith, Billy Joe Saunders, and Caleb Plant) to win all four titles at super middleweight, a feat he achieved inside 12 months.

[33] His sixth-round technical knockout (TKO) win over Luciano Leonel Cuello for the WBC Silver light middleweight title was held at the Vicente Fernández Arena.

[35] He next faced the former WBC welterweight champion Carlos Baldomir at the Staples Center in Los Angeles, California, on the Shane Mosley vs. Sergio Mora undercard.

[43] On 17 September 2011, Álvarez successfully defended that same WBC title against The Contender competitor Alfonso Gómez at the Staples Center in Los Angeles, winning via TKO in the sixth round.

Álvarez was scheduled to defend his title against former welterweight titlist Victor Ortiz in the main event of a Showtime pay-per-view (PPV) card dubbed 'Knockout Kings' at the MGM Grand Garden Arena.

However, on 23 June, Ortiz was unable to defeat underdog Josesito López in what was supposed to be a "tune-up" fight at the Staples Center in Los Angeles, losing due to referee stoppage (broken jaw) and cancelling his bout with Álvarez as a result.

[64][65][66][67] On 9 January 2014, Golden Boy chief executive Richard Schaefer confirmed a deal had been made for a fight between Álvarez and 31 year old Mexican boxer Alfredo Angulo (22–3, 18 KOs) to take place on 8 March 2014, on Showtime PPV at the MGM Grand in Las Vegas.

"[76][77] In January 2015, Oscar De La Hoya announced that Álvarez and James Kirkland (32–1, 28 KOs) had agreed to fight each other although no date or venue was set, in a non-title light middleweight bout.

[83] On 21 November 2015, Álvarez won the WBC, Ring and lineal middleweight titles with a unanimous decision victory over Miguel Cotto in front of a sold-out crowd of 11,274 at the Mandalay Bay Events Center in Las Vegas.

[95] On 24 June, it was announced that Álvarez was to drop the extra pound to 154 and challenge 27 year old WBO champion Liam Smith (23–0–1, 13 KOs) from England on 17 September 2016, in the main event of a card on HBO PPV.

On 18 July, Golden Boy Promotions announced the bout would take place at AT&T Stadium in Arlington, Texas, after the MGM Grand in Las Vegas was the other venue looking to host the fight.

"[105][106] On 18 December, Julio César Chávez Sr. spoke about the ongoing negotiations, saying Golden Boy were offering his son a small amount for the potential big PPV fight.

[127] This was the first boxing match to generate over a million PPV buys that didn't include Mayweather, Pacquiao or De La Hoya since 2002, which saw Lennox Lewis retain his heavyweight world titles against Mike Tyson.

[130] De La Hoya later revealed in an interview with ESPN that the fight would also take place at the full middleweight limit of 160 lbs with no rehydration clauses, meaning Golovkin and Álvarez would be able to gain an unlimited amount of weight following the weigh in.

[135] On 22 August, IBF president Daryl Peoples announced that they would be dropping the mandatory second day weigh in for unification fights, meaning neither fighter is required to participate, however they would still encourage them to do so.

On 19 September, Golden Boy Promotions president Eric Gomez told ESPN that everyone on their side was interested in the rematch and they would hold discussions with Tom Loeffler in the coming days.

[189][190] Hours later, De La Hoya confirmed via his Twitter account that terms had been agreed and the fight would indeed take place on 15 September at the T-Mobile Arena in Las Vegas, Nevada.

Doug Fischer wrote, "We posed the question to the ratings panel, which, in a landslide, voted in favor the magazine's 160-pound championship being up for grabs when the two stars clash at T-Mobile Arena in Las Vegas.

[210][211] On 13 September 2019, Álvarez announced via social media that he would move up two weight classes to challenge WBO light heavyweight titleholder Sergey Kovalev on 2 November 2019, at the MGM Grand Garden Arena in Las Vegas.

[214] He joined Thomas Hearns, Sugar Ray Leonard, and Mike McCallum as the only former junior middleweight champions in history to win a title at light heavyweight.

[229] On the night, Álvarez controlled the action over twelve rounds, inflicting Smith with a detached left biceps injury as he won by unanimous decision with scores of 119–109, 119–109, 117–111.

[230][231] It was announced on 20 January 2021 that Álvarez would be defending his titles against WBC mandatory challenger Avni Yıldırım on 27 February at the Hard Rock Stadium, Miami Gardens, Florida.

[232] The bout attracted criticism due to many perceiving Yıldırım, who had not been in the ring since he lost a technical split decision to Anthony Dirrell two years prior in February 2019, to be vastly over-matched.

[233] Álvarez, who was mandated to face Yıldırım in order to retain the WBC title despite being heavily favored, was dismissive of the critics, saying "I really don't have to give any explanation because they're never gonna be happy with anything...

He had knocked his opponent to the canvas with a left hook right uppercut combination in the penultimate round, before closing in to drop Plant again, prompting referee Russell Mora to call off the bout.

[255] Instead, it was announced on 25 February 2022 that Álvarez had signed a two-fight deal with Matchroom Boxing; the first fight would see him returning to the light heavyweight division to challenge undefeated WBA (Super) champion Dmitry Bivol on 7 May in a bout that would be televised as sports streaming service DAZN's first pay-per-view offering in the United States and Canada.

[260][261][262] Despite the widespread public opinion that Bivol was the deserved winner, Álvarez initially disagreed with this notion, stating in his post-fight interview: "I don't feel like I lost the fight...

"[260] Despite this, a rematch between Álvarez and Bivol did not materialize immediately, as the former opted to face WBA (Super) and IBF middleweight champion Gennady Golovkin in a trilogy bout as his opponent for his next fight instead.

[267] On 14 March 2023, it was announced that Álvarez would be making the second defense of his undisputed super middleweight titles against WBO interim champion John Ryder at Estadio Akron in his hometown of Guadalajara, Mexico on 6 May.

[287][288][289] He is an avid car collector, owning a Ferrari LaFerrari, a Bugatti Chiron, a Lamborghini Aventador SVJ, a Shelby Mustang, a Mercedes-AMG G 63 6x6, a Rolls Royce Ghost, and a Tesla Model X.