"Scar Tissue" is the first single from American rock band Red Hot Chili Peppers' seventh studio album, Californication (1999).

"Scar Tissue" is considered to be representative of the new, more melodic rock sound the band experimented with on Californication (in contrast with the psychedelic One Hot Minute, and dry funk of Blood Sugar Sex Magik).

In 2004, lead vocalist Anthony Kiedis published an autobiography titled after the song.

They are traveling in a rusty wreck and playing broken instruments on the comeback trail.

[5] American band Mr. Bungle performed a mock version of the song in 1999, as part of a Halloween concert parodying Red Hot Chili Peppers.